Pseudomonas aeruginosa 2192, PA2G_05379

Gene Feature Overview

Strain	Pseudomonas aeruginosa 2192 GCF_000152545.1|latest
Locus Tag	PA2G_05379
Name
Replicon	chromosome
Genomic location	6013900 - 6015291 (+ strand)

Cross-References

RefSeq	ZP_04937840.1
GI	254244518
NCBI Locus Tag	PA2G_05379
UniProtKB Acc	A3LKH8
UniProtKB ID	A3LKH8_PSEAE

Product

Feature Type	CDS
Coding Frame	1
Product Name	membrane protein
Synonyms
Evidence for Translation
Charge (pH 7)	-2.59
Kyte-Doolittle Hydrophobicity Value	-0.250
Molecular Weight (kDa)	49.7
Isoelectric Point (pI)	6.26

Subcellular localization

Individual Mappings	Localization Confidence PMID Outer Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
3DWO	MEMBRANE PROTEIN	07/22/08	Crystal structure of a Pseudomonas aeruginosa FadL homologue	Pseudomonas aeruginosa	2.2	X-RAY DIFFRACTION	99.8

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name	Source Accession	Source DB	Version	Target Accession	Target Description	Percent Identity	Alignment Length	E-Value
(Hydroxyethyloxy)Tri(Ethyloxy)Octane	DB04233	DrugBank	5.1.4	Q9HVJ6	Probable outer membrane protein	99.8	463	2.2e-275

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004247 (347 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2G_05379 Search term: membrane protein

Human Homologs

References