Pseudomonas aeruginosa 2192, PA2G_05879

Gene Feature Overview

Strain	Pseudomonas aeruginosa 2192 GCF_000152545.1|latest
Locus Tag	PA2G_05879
Name
Replicon	chromosome
Genomic location	6566275 - 6567171 (- strand)

Cross-References

RefSeq	ZP_04938322.1
GI	254245000
NCBI Locus Tag	PA2G_05879
UniProtKB Acc	A3LLW0
UniProtKB ID	A3LLW0_PSEAE

Product

Feature Type	CDS
Coding Frame	1
Product Name	3-hydroxyisobutyrate dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-4.86
Kyte-Doolittle Hydrophobicity Value	0.236
Molecular Weight (kDa)	30.7
Isoelectric Point (pI)	5.30

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
3OBB	OXIDOREDUCTASE	08/06/10	Crystal structure of a possible 3-hydroxyisobutyrate Dehydrogenase from pseudomonas aeruginosa pao1	Pseudomonas aeruginosa	2.2	X-RAY DIFFRACTION	99.3
3Q3C	OXIDOREDUCTASE	12/21/10	Crystal structure of a serine dehydrogenase from Pseudomonas aeruginosa pao1 in complex with NAD	Pseudomonas aeruginosa	2.299	X-RAY DIFFRACTION	99.3

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000717 (830 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2G_05879 Search term: 3-hydroxyisobutyrate dehydrogenase

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000265395 3-hydroxyisobutyrate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4907] E-value: 4.4e-64 Percent Identity: 45.3

References