Pseudomonas aeruginosa PAO1, PA1862 (modB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1862
Name
modB
Replicon chromosome
Genomic location 2021712 - 2022398 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250553.1
GI 15597059
Affymetrix PA1862_modB_at
Entrez 882065
GenBank AAG05251.1
INSDC AAG05251.1
NCBI Locus Tag PA1862
protein_id(GenBank) gb|AAG05251.1|AE004612_5|gnl|PseudoCAP|PA1862
TIGR NTL03PA01863
UniParc UPI00000C54DA
UniProtKB Acc Q9I2N3
UniProtKB ID Q9I2N3_PSEAE
UniRef100 UniRef100_Q9I2N3
UniRef50 UniRef50_Q08382
UniRef90 UniRef90_Q9I2N3

Product

Feature Type CDS
Coding Frame 1
Product Name
molybdenum transport protein ModB
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 1.71
Kyte-Doolittle Hydrophobicity Value 0.798
Molecular Weight (kDa) 24.4
Isoelectric Point (pI) 8.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 572 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003541 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1862
Search term: modB

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Characterization of genes involved in molybdenum transport in Azotobacter vinelandii.
Luque F, Mitchenall LA, Chapman M, Christine R, Pau RN
Mol Microbiol 1993 Feb;7(3):447-59
PubMed ID: 8384683
Molecular analysis of the molybdate uptake operon, modABCD, of Escherichia coli and modR, a regulatory gene.
Walkenhorst HM, Hemschemeier SK, Eichenlaub R
Microbiol Res 1995 Nov;150(4):347-61
PubMed ID: 8564363