Pseudomonas aeruginosa PAO1, PA2604

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2604
Name
Synonym: yccA
Replicon chromosome
Genomic location 2947803 - 2948471 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251294.1
GI 15597800
Affymetrix PA2604_at
DNASU PaCD00007121
Entrez 882310
GenBank AAG05992.1
INSDC AAG05992.1
NCBI Locus Tag PA2604
protein_id(GenBank) gb|AAG05992.1|AE004689_4|gnl|PseudoCAP|PA2604
TIGR NTL03PA02604
UniParc UPI000013BE74
UniProtKB Acc Q03268
UniProtKB ID Y2604_PSEAE
UniRef100 UniRef100_Q03268
UniRef50 UniRef50_Q03268
UniRef90 UniRef90_Q03268

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) 1.21
Kyte-Doolittle Hydrophobicity Value 0.863
Molecular Weight (kDa) 24.1
Isoelectric Point (pI) 8.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 224 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002947 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2604

Human Homologs

Ensembl 110, assembly GRCh38.p14
transmembrane BAX inhibitor motif containing 4 [Source:HGNC Symbol;Acc:HGNC:24257]
E-value: 1.5e-08
Percent Identity: 27.9
Ensembl 110, assembly GRCh38.p14
transmembrane BAX inhibitor motif containing 4 [Source:HGNC Symbol;Acc:HGNC:24257]
E-value: 1.5e-08
Percent Identity: 27.9

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295