Pseudomonas aeruginosa PAO1, PA2774 (tse4)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2774
Name
tse4
Replicon chromosome
Genomic location 3132229 - 3132816 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251464.1
GI 15597970
Affymetrix PA2774_at
Entrez 882745
GenBank AAG06162.1
INSDC AAG06162.1
NCBI Locus Tag PA2774
protein_id(GenBank) gb|AAG06162.1|AE004705_4|gnl|PseudoCAP|PA2774
TIGR NTL03PA02774
UniParc UPI00000C57FA
UniProtKB Acc Q9I069
UniProtKB ID Q9I069_PSEAE
UniRef100 UniRef100_W0YTP0
UniRef50 UniRef50_Q4K6P4
UniRef90 UniRef90_Q02NT1

Product

Feature Type CDS
Coding Frame 1
Product Name
Tse4
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.95
Kyte-Doolittle Hydrophobicity Value 0.494
Molecular Weight (kDa) 19.2
Isoelectric Point (pI) 9.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 2 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002795 (319 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2774
Search term: tse4
Search term: Tse4

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Genetically distinct pathways guide effector export through the type VI secretion system.
Whitney JC, Beck CM, Goo YA, Russell AB, Harding BN, De Leon JA, Cunningham DA, Tran BQ, Low DA, Goodlett DR, Hayes CS, Mougous JD
Mol Microbiol 2014 May;92(3):529-42
PubMed ID: 24589350