Pseudomonas aeruginosa PAO1, PA0247 (pobA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0018659 4-hydroxybenzoate 3-monooxygenase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 2465205 Reviewed by curator
Biological Process GO:0043639 benzoate catabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 2465205 Reviewed by curator
Molecular Function GO:0018659 4-hydroxybenzoate 3-monooxygenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02360
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0043639 benzoate catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02360
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050660 flavin adenine dinucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02360
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0071949 FAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01494
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00362 Benzoate degradation 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Aromatic compound catabolism ECO:0000037
not_recorded
PseudoCyc 4-HYDROXYMANDELATE-DEGRADATION-PWY 4-hydroxymandelate degradation 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01220 Degradation of aromatic compounds 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF01494 FAD binding domain IPR002938 FAD-binding domain 2 343 3.0E-100
PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature - - 310 328 1.5E-32
Gene3D G3DSA:3.30.9.10 - - - 73 388 0.0
SUPERFAMILY SSF51905 FAD/NAD(P)-binding domain IPR036188 FAD/NAD(P)-binding domain superfamily 1 389 9.43E-59
PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature - - 293 309 1.5E-32
SUPERFAMILY SSF54373 FAD-linked reductases, C-terminal domain - - 175 275 2.47E-46
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 2 351 0.0
PANTHER PTHR43476 3-(3-HYDROXY-PHENYL)PROPIONATE/3-HYDROXYCINNAMIC ACID HYDROXYLASE - - 3 328 6.8E-31
PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature - - 151 166 1.5E-32
PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature - - 278 293 1.5E-32
PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature - - 4 26 1.5E-32
NCBIfam TIGR02360 JCVI: 4-hydroxybenzoate 3-monooxygenase IPR012733 4-hydroxybenzoate 3-monooxygenase 1 390 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.