Pseudomonas aeruginosa PAO1, PA0609 (trpE)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0000162	tryptophan biosynthetic process	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	2153661	Reviewed by curator
Molecular Function	GO:0004049	anthranilate synthase activity	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	2153661	Reviewed by curator
Biological Process	GO:0006744	ubiquinone biosynthetic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0006091	generation of precursor metabolites and energy	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0006558	L-phenylalanine metabolic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0006520	cellular amino acid metabolic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0000162	tryptophan biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00564	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0004049	anthranilate synthase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00564	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0009058	biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:G3DSA:3.60.120.10	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class Energy metabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae01230	Biosynthesis of amino acids	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae02025	Biofilm formation - Pseudomonas aeruginosa	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Ubiquinone biosynthesis		ECO:0000037 not_recorded
PseudoCyc	TRPSYN-PWY	L-tryptophan biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCAP		Phenylalanine metabolism		ECO:0000037 not_recorded
MetaCyc		acridone alkaloid biosynthesis	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	pae02024	Quorum sensing	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00400	Phenylalanine, tyrosine and tryptophan biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	COMPLETE-ARO-PWY	superpathway of aromatic amino acid biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
MetaCyc		4-hydroxy-2(1<i>H</i>)-quinolone biosynthesis	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
PseudoCyc	PWY-6661	4-hydroxy-2(1H)-quinolone biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01130	Biosynthesis of antibiotics	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	ALL-CHORISMATE-PWY	superpathway of chorismate metabolism	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	PWY-6660	2-heptyl-3-hydroxy-4(1H)-quinolone biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR00095	Anthranilate synthase component I signature	IPR019999	Anthranilate synthase component I-like	433	447	1.1E-25
PRINTS	PR00095	Anthranilate synthase component I signature	IPR019999	Anthranilate synthase component I-like	418	432	1.1E-25
PRINTS	PR00095	Anthranilate synthase component I signature	IPR019999	Anthranilate synthase component I-like	324	337	1.1E-25
SUPERFAMILY	SSF56322	ADC synthase	IPR005801	ADC synthase	14	485	0.0
PANTHER	PTHR11236	AMINOBENZOATE/ANTHRANILATE SYNTHASE	IPR019999	Anthranilate synthase component I-like	13	490	0.0
Pfam	PF00425	chorismate binding enzyme	IPR015890	Chorismate-utilising enzyme, C-terminal	223	476	4.9E-91
NCBIfam	TIGR00564	JCVI: anthranilate synthase component I	IPR005256	Anthranilate synthase component I, PabB-like	26	484	0.0
Gene3D	G3DSA:3.60.120.10	Anthranilate synthase	IPR005801	ADC synthase	1	491	0.0
PRINTS	PR00095	Anthranilate synthase component I signature	IPR019999	Anthranilate synthase component I-like	338	351	1.1E-25
Pfam	PF04715	Anthranilate synthase component I, N terminal region	IPR006805	Anthranilate synthase component I, N-terminal	27	168	8.3E-31

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.