Pseudomonas aeruginosa PAO1, PA0679 (hxcP)

Annotation Updates

Date	Description	Acknowledgements
May 8, 2015	New gene name: hxcP. New product name: HxcP. New product name confidence: Class 1.	Rome Voulhoux, CNRS, Marseille, France
Jun 10, 2004	Annotation of gene described as hypothetical protein (Class 4). New evidence reference (PubMed ID): 11985723. New homology added: 38% identical and 63% similar to ExeC[Aeromona hydrophila] Genomic context: Ribosome binding site: AGGAGAG from -13 to -7 (Kolaskar and Reddy rule for ATG: 20). New structure features: Transmembrane domain predicted between residues 15 and 34. Most probably a bitopic inner membrane protein (Nin-Cout), as the members of the GspC family. Other hydrophobic region between residues 70 and 94. New comments: Hxc proteins are involved in the secretion of alkaline phosphatase. hxc gene cluster is under phosphate regulation. May belong to the GspC family (general secretory pathway protein C).	Raymond C. Lo and Fiona S.L. Brinkman, Simon Fraser University, Canada (based on literature review);