Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1156
|
Name |
nrdA
|
Replicon | chromosome |
Genomic location | 1251418 - 1254309 (- strand) |
RefSeq | NP_249847.1 |
GI | 15596353 |
Affymetrix | PA1156_nrdA_at |
Entrez | 877716 |
GenBank | AAG04545.1 |
INSDC | AAG04545.1 |
NCBI Locus Tag | PA1156 |
protein_id(GenBank) | gb|AAG04545.1|AE004545_8|gnl|PseudoCAP|PA1156 |
TIGR | NTL03PA01157 |
UniParc | UPI00000C527A |
UniProtKB Acc | Q9I4I1 |
UniProtKB ID | Q9I4I1_PSEAE |
UniRef100 | UniRef100_W0YQ69 |
UniRef50 | UniRef50_Q607W9 |
UniRef90 | UniRef90_A4VK21 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
NrdA, catalytic component of class Ia ribonucleotide reductase
|
Synonyms |
NrdA, catalytic component of class Ia ribonucleotide reductase |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (107.11 kDa, PMID:21751344)
|
Charge (pH 7) | -14.68 |
Kyte-Doolittle Hydrophobicity Value | -0.309 |
Molecular Weight (kDa) | 107.1 |
Isoelectric Point (pI) | 5.69 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
5IM3 | OXIDOREDUCTASE | 03/05/16 | Crystal structure of the class I ribonucleotide reductase from Pseudomonas aeruginosa in complex with dATP | Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) | 2.298 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 603 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001115 (534 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1156
Search term: nrdA
|
Ensembl
110, assembly
GRCh38.p14
|
ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451]
E-value:
2.9e-157
Percent Identity:
41.0
|
Ribonucleotide reductase modularity: Atypical duplication of the ATP-cone domain in Pseudomonas aeruginosa.
Torrents E, Westman M, Sahlin M, Sjöberg BM
J Biol Chem 2006 Sep 1;281(35):25287-96
PubMed ID: 16829681
|
Promoter identification and expression analysis of Salmonella typhimurium and Escherichia coli nrdEF operons encoding one of two class I ribonucleotide reductases present in both bacteria.
Jordan A, Aragall E, Gibert I, Barbe J
Mol Microbiol 1996 Feb;19(4):777-90
PubMed ID: 8820648
|
Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis.
Stephens RS, Kalman S, Lammel C, Fan J, Marathe R, Aravind L, Mitchell W, Olinger L, Tatusov RL, Zhao Q, Koonin EV, Davis RW
Science 1998 Oct 23;282(5389):754-9
PubMed ID: 9784136
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
|