Pseudomonas aeruginosa PAO1, PA1250 (aprI)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0004866	endopeptidase inhibitor activity	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF50882	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0010951	negative regulation of endopeptidase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PR01274	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008191	metalloendopeptidase inhibitor activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PR01274	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Secreted Factors (toxins, enzymes, alginate) Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Gene3D	G3DSA:2.40.128.10	-	-	-	26	131	4.8E-32
PRINTS	PR01274	Metalloprotease inhibitor signature	IPR022815	Protease inhibitor	90	103	5.9E-17
PRINTS	PR01274	Metalloprotease inhibitor signature	IPR022815	Protease inhibitor	68	79	5.9E-17
Pfam	PF02974	Protease inhibitor Inh	IPR021140	Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19	32	128	7.9E-23
SUPERFAMILY	SSF50882	beta-Barrel protease inhibitors	IPR016085	Protease inhibitor, beta-barrel domain	26	128	3.14E-26
PRINTS	PR01274	Metalloprotease inhibitor signature	IPR022815	Protease inhibitor	107	120	5.9E-17
PRINTS	PR01274	Metalloprotease inhibitor signature	IPR022815	Protease inhibitor	26	42	5.9E-17

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.