Pseudomonas aeruginosa PAO1, PA1502 (gcl)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0009028 tartronate-semialdehyde synthase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 18176558 Reviewed by curator
Biological Process GO:0046296 glycolate catabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 4892366 Reviewed by curator
Biological Process GO:0009436 glyoxylate catabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 4892366 Reviewed by curator
Molecular Function GO:0030976 thiamine pyrophosphate binding
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 18176558 Reviewed by curator
Molecular Function GO:0030976 thiamine pyrophosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009436 glyoxylate catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01504
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0009028 tartronate-semialdehyde synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01504
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Central intermediary metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00630 Glyoxylate and dicarboxylate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Glyoxylate and dicarboxylate metabolism ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.1220 - - - 193 358 5.8E-51
NCBIfam TIGR01504 JCVI: glyoxylate carboligase IPR006397 Glyoxylate carboligase 2 590 0.0
FunFam G3DSA:3.40.50.1220:FF:000008 Acetolactate synthase - - 186 361 5.3E-58
Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain IPR011766 Thiamine pyrophosphate enzyme, TPP-binding 393 553 3.7E-33
Gene3D G3DSA:3.40.50.970 - - - 359 582 6.8E-70
Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain 5 172 4.1E-49
PANTHER PTHR18968 THIAMINE PYROPHOSPHATE ENZYMES IPR045229 Thiamine pyrophosphate enzyme 3 559 0.0
Gene3D G3DSA:3.40.50.970 - - - 1 185 2.3E-50
SUPERFAMILY SSF52467 DHS-like NAD/FAD-binding domain IPR029035 DHS-like NAD/FAD-binding domain superfamily 161 350 4.24E-48
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 3 184 2.4E-48
FunFam G3DSA:3.40.50.970:FF:000007 Acetolactate synthase - - 1 187 4.7E-67
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 369 567 4.42E-51
CDD cd07035 TPP_PYR_POX_like - - 8 163 4.93566E-55
Pfam PF00205 Thiamine pyrophosphate enzyme, central domain IPR012000 Thiamine pyrophosphate enzyme, central domain 194 328 4.9E-37

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.