Pseudomonas aeruginosa PAO1, PA1518

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0033971 hydroxyisourate hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02962
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006144 purine nucleobase metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02962
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Hypothetical, unclassified, unknown Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00576 HIUase/Transthyretin family IPR023416 Transthyretin/hydroxyisourate hydrolase domain 13 125 2.5E-35
SUPERFAMILY SSF49472 Transthyretin (synonym: prealbumin) IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily 6 126 3.4E-43
NCBIfam TIGR02962 JCVI: hydroxyisourate hydrolase IPR014306 Hydroxyisourate hydrolase 11 126 1.4E-39
PRINTS PR00189 Transthyretin signature IPR000895 Transthyretin/hydroxyisourate hydrolase 12 32 1.2E-7
PANTHER PTHR10395 URICASE AND TRANSTHYRETIN-RELATED IPR023416 Transthyretin/hydroxyisourate hydrolase domain 9 126 1.2E-30
PRINTS PR00189 Transthyretin signature IPR000895 Transthyretin/hydroxyisourate hydrolase 104 126 1.2E-7
FunFam G3DSA:2.60.40.180:FF:000005 5-hydroxyisourate hydrolase - - 7 126 1.3E-56
CDD cd05822 TLP_HIUase IPR014306 Hydroxyisourate hydrolase 11 126 1.18671E-56
Gene3D G3DSA:2.60.40.180 Transthyretin/hydroxyisourate hydrolase domain IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily 5 126 1.8E-40

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.