Pseudomonas aeruginosa PAO1, PA1521

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008892 guanine deaminase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01303
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008270 zinc ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01303
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006147 guanine catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01303
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:2.30.40.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01979
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Purine metabolism ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:2.30.40.10 Urease, subunit C, domain 1 IPR011059 Metal-dependent hydrolase, composite domain superfamily 9 424 0.0
Pfam PF01979 Amidohydrolase family IPR006680 Amidohydrolase-related 69 430 4.3E-69
Gene3D G3DSA:3.20.20.140 - - - 72 390 0.0
NCBIfam TIGR02967 JCVI: guanine deaminase IPR014311 Guanine deaminase 28 427 0.0
FunFam G3DSA:3.20.20.140:FF:000022 Guanine deaminase - - 72 373 0.0
SUPERFAMILY SSF51338 Composite domain of metallo-dependent hydrolases IPR011059 Metal-dependent hydrolase, composite domain superfamily 29 88 2.07E-10
SUPERFAMILY SSF51556 Metallo-dependent hydrolases IPR032466 Metal-dependent hydrolase 71 374 4.0E-104
PANTHER PTHR11271 GUANINE DEAMINASE - - 3 433 7.8E-119
CDD cd01303 GDEase IPR014311 Guanine deaminase 8 427 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.