Pseudomonas aeruginosa PAO1, PA1532 (dnaX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0030337 DNA polymerase processivity factor activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 7494000 Reviewed by curator
Cellular Component GO:0043846 DNA polymerase III, clamp loader complex
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 15611049 Reviewed by curator
Biological Process GO:0006260 DNA replication
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 15611049 Reviewed by curator
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00300
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003887 DNA-directed DNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02397
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48019
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0009360 DNA polymerase III complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02397
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02397
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae03030 DNA replication 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae03440 Homologous recombination 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00009 AAA - - 19 170 3.91144E-14
Pfam PF13177 DNA polymerase III, delta subunit - - 20 178 6.1E-45
Gene3D G3DSA:1.20.272.10 - - - 243 361 1.5E-40
MobiDBLite mobidb-lite consensus disorder prediction - - 444 472 -
PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature IPR001270 ClpA/B family 41 59 1.9E-5
MobiDBLite mobidb-lite consensus disorder prediction - - 367 394 -
SUPERFAMILY SSF48019 post-AAA+ oligomerization domain-like IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal 243 362 1.36E-33
FunFam G3DSA:1.10.8.60:FF:000013 DNA polymerase III subunit gamma/tau - - 179 242 8.6E-25
Gene3D G3DSA:1.10.8.60 - - - 180 242 3.8E-22
CDD cd18137 HLD_clamp_pol_III_gamma_tau IPR045085 DNA polymerase III, subunit gamma/tau, helical lid domain 178 242 7.06824E-26
Gene3D G3DSA:3.30.300.150 DNA polymerase III, tau subunit, domain V IPR038249 DNA polymerase III, tau subunit, domain V superfamily 546 659 2.3E-30
PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature IPR001270 ClpA/B family 124 142 1.9E-5
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 1 177 8.1E-67
FunFam G3DSA:3.40.50.300:FF:000014 DNA polymerase III subunit gamma/tau - - 1 177 6.4E-86
FunFam G3DSA:3.30.300.150:FF:000002 DNA polymerase III subunit gamma/tau - - 537 659 1.3E-67
FunFam G3DSA:1.20.272.10:FF:000003 DNA polymerase III subunit gamma/tau - - 243 361 5.8E-48
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 37 179 7.6E-7
NCBIfam TIGR02397 JCVI: DNA polymerase III subunit gamma/tau IPR012763 DNA polymerase III, subunit gamma/ tau, N-terminal 3 355 2.5E-130
Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha IPR021029 DNA polymerase III, tau subunit, domain V 556 671 4.4E-16
MobiDBLite mobidb-lite consensus disorder prediction - - 456 472 -
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 29 222 2.41E-58
Pfam PF12169 DNA polymerase III subunits gamma and tau domain III IPR022754 DNA polymerase III, gamma subunit, domain III 233 359 4.9E-31
PANTHER PTHR11669 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT - - 7 291 4.8E-66
MobiDBLite mobidb-lite consensus disorder prediction - - 499 518 -
MobiDBLite mobidb-lite consensus disorder prediction - - 503 518 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.