Pseudomonas aeruginosa PAO1, PA2005 (hbcR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000976 transcription regulatory region sequence-specific DNA binding
IDA
Inferred from Direct Assay 		ECO:0000096
electrophoretic mobility shift assay evidence		 26311173 Reviewed by curator
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008134 transcription factor binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01590
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.40.50.300:FF:000006 DNA-binding transcriptional regulator NtrC - - 149 329 5.7E-70
PANTHER PTHR32071 TRANSCRIPTIONAL REGULATORY PROTEIN - - 85 470 4.7E-117
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 143 329 2.9E-64
SMART SM00091 pas_2 IPR000014 PAS domain 19 86 0.0065
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 158 397 1.36E-63
Pfam PF00158 Sigma-54 interaction domain IPR002078 RNA polymerase sigma factor 54 interaction domain 159 326 4.8E-63
Pfam PF02954 Bacterial regulatory protein, Fis family IPR002197 DNA binding HTH domain, Fis-type 426 463 2.4E-12
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 178 323 9.4E-9
CDD cd00130 PAS IPR000014 PAS domain 28 117 0.00292396
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 11 116 2.44E-12
Pfam PF08448 PAS fold IPR013656 PAS fold-4 26 116 5.0E-7
PRINTS PR01590 FIS bacterial regulatory protein HTH signature IPR002197 DNA binding HTH domain, Fis-type 449 469 1.4E-8
PRINTS PR01590 FIS bacterial regulatory protein HTH signature IPR002197 DNA binding HTH domain, Fis-type 432 449 1.4E-8
Gene3D G3DSA:1.10.10.60 - - - 419 472 1.6E-13
Gene3D G3DSA:3.30.450.20 PAS domain - - 6 118 1.2E-9
Gene3D G3DSA:1.10.8.60 - - - 330 401 1.4E-17
CDD cd00009 AAA - - 167 329 1.68546E-22
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 369 468 5.02E-13

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.