Pseudomonas aeruginosa PAO1, PA2526 (muxC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00702
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00702
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0022857 transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00702
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Membrane proteins Other PAO1 genes in this class
Antibiotic resistance and susceptibility Other PAO1 genes in this class
Transport of small molecules Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF82693 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains - - 40 134 2.96E-22
Gene3D G3DSA:3.30.70.1430 Multidrug efflux transporter AcrB pore domain - - 40 805 0.0
SUPERFAMILY SSF82693 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains - - 558 649 4.97E-12
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 387 411 6.3E-88
Gene3D G3DSA:1.20.1640.10 Multidrug efflux transporter AcrB transmembrane domain - - 509 1011 0.0
FunFam G3DSA:3.30.70.1430:FF:000001 Efflux pump membrane transporter - - 40 140 1.7E-30
Gene3D G3DSA:3.30.2090.10 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains 709 797 0.0
Pfam PF00873 AcrB/AcrD/AcrF family IPR001036 Acriflavin resistance protein 6 1013 0.0
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 359 380 6.3E-88
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 611 625 6.3E-88
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 38 56 6.3E-88
Gene3D G3DSA:3.30.70.1320 Multidrug efflux transporter AcrB pore domain like - - 135 327 0.0
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 440 463 6.3E-88
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 545 562 6.3E-88
SUPERFAMILY SSF82714 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains 183 268 1.44E-15
FunFam G3DSA:1.20.1640.10:FF:000001 Efflux pump membrane transporter - - 302 504 6.8E-72
SUPERFAMILY SSF82866 Multidrug efflux transporter AcrB transmembrane domain - - 794 1019 1.15E-43
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 10 34 6.3E-88
SUPERFAMILY SSF82714 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains 708 791 4.58E-16
Gene3D G3DSA:3.30.70.1440 Multidrug efflux transporter AcrB pore domain - - 658 857 0.0
Gene3D G3DSA:3.30.2090.10 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains 180 274 0.0
SUPERFAMILY SSF82866 Multidrug efflux transporter AcrB transmembrane domain - - 294 493 6.41E-48
PANTHER PTHR32063 - IPR001036 Acriflavin resistance protein 1 1020 0.0
SUPERFAMILY SSF82693 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains - - 135 326 5.23E-19
Gene3D G3DSA:1.20.1640.10 Multidrug efflux transporter AcrB transmembrane domain - - 9 508 0.0
Gene3D G3DSA:3.30.70.1430 Multidrug efflux transporter AcrB pore domain - - 563 657 0.0
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 332 355 6.3E-88
PRINTS PR00702 Acriflavin resistance protein family signature IPR001036 Acriflavin resistance protein 465 488 6.3E-88

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.