Pseudomonas aeruginosa PAO1, PA2580

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2580
Name
Synonym: mdaB
Replicon chromosome
Genomic location 2916158 - 2916748 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251270.1
GI 15597776
Affymetrix PA2580_at
DNASU PaCD00007114
Entrez 879141
GenBank AAG05968.1
INSDC AAG05968.1
NCBI Locus Tag PA2580
protein_id(GenBank) gb|AAG05968.1|AE004686_6|gnl|PseudoCAP|PA2580
TIGR NTL03PA02580
UniParc UPI00000C574E
UniProtKB Acc Q9I0Q6
UniProtKB ID Q9I0Q6_PSEAE
UniRef100 UniRef100_Q9I0Q6
UniRef50 UniRef50_Q09677
UniRef90 UniRef90_V6AF55

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 2.43
Kyte-Doolittle Hydrophobicity Value -0.348
Molecular Weight (kDa) 22.0
Isoelectric Point (pI) 8.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 126 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002966 (491 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2580

Human Homologs

References

A general genetic approach in Escherichia coli for determining the mechanism(s) of action of tumoricidal agents: application to DMP 840, a tumoricidal agent.
Chatterjee PK, Sternberg NL
Proc Natl Acad Sci U S A 1995 Sep 12;92(19):8950-4
PubMed ID: 7568050
Pseudomonas aeruginosa MdaB and WrbA are water-soluble two-electron quinone oxidoreductases with the potential to defend against oxidative stress.
Green LK, La Flamme AC, Ackerley DF
J Microbiol 2014 Sep;52(9):771-7
PubMed ID: 25085734