Pseudomonas aeruginosa PAO1, PA2612 (serS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 7537870 Reviewed by curator
Biological Process GO:0044267 cellular protein metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004828 serine-tRNA ligase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 7537870 Reviewed by curator
Biological Process GO:0006434 seryl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00176
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00587
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00587
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004828 serine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00176
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00176
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00176
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class
Translation, post-translational modification, degradation Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Glycine, serine and threonine metabolism ECO:0000037
not_recorded
PseudoCAP Aminoacyl-tRNA biosynthesis ECO:0000037
not_recorded
PseudoCyc TRNA-CHARGING-PWY tRNA charging 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR43697 SERYL-TRNA SYNTHETASE - - 1 425 0.0
PRINTS PR00981 Seryl-tRNA synthetase signature IPR002317 Serine-tRNA ligase, type1 318 331 7.7E-34
PIRSF PIRSF001529 Ser-tRNA_ligase IPR002317 Serine-tRNA ligase, type1 1 426 0.0
PRINTS PR00981 Seryl-tRNA synthetase signature IPR002317 Serine-tRNA ligase, type1 278 291 7.7E-34
Coils Coil Coil - - 75 95 -
Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) 218 402 4.8E-36
Hamap MF_00176 Serine--tRNA ligase [serS]. IPR002317 Serine-tRNA ligase, type1 1 424 41.258781
Gene3D G3DSA:1.10.287.40 - IPR042103 Serine-tRNA synthetase, type1, N-terminal domain superfamily 1 104 5.0E-31
NCBIfam TIGR00414 JCVI: serine--tRNA ligase IPR002317 Serine-tRNA ligase, type1 1 419 0.0
Pfam PF02403 Seryl-tRNA synthetase N-terminal domain IPR015866 Serine-tRNA synthetase, type1, N-terminal 1 107 1.6E-30
Coils Coil Coil - - 30 50 -
PRINTS PR00981 Seryl-tRNA synthetase signature IPR002317 Serine-tRNA ligase, type1 335 351 7.7E-34
Gene3D G3DSA:3.30.930.10 Bira Bifunctional Protein; Domain 2 IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 105 425 0.0
PRINTS PR00981 Seryl-tRNA synthetase signature IPR002317 Serine-tRNA ligase, type1 266 278 7.7E-34
SUPERFAMILY SSF55681 Class II aaRS and biotin synthetases IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 116 423 2.49E-102
SUPERFAMILY SSF46589 tRNA-binding arm IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm 1 112 6.28E-31
CDD cd00770 SerRS_core IPR033729 Serine-tRNA ligase catalytic core domain 119 419 0.0
PRINTS PR00981 Seryl-tRNA synthetase signature IPR002317 Serine-tRNA ligase, type1 353 369 7.7E-34

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.