Pseudomonas aeruginosa PAO1, PA2739 (pheT)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006259 DNA metabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0004817 cysteine-tRNA ligase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0044267 cellular protein metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00874
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006432 phenylalanyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR10947
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000049 tRNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02796
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00874
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004826 phenylalanine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR10947
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003723 RNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03483
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Phenylalanine, tyrosine and tryptophan biosynthesis ECO:0000037
not_recorded
PseudoCyc TRNA-CHARGING-PWY tRNA charging 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Aminoacyl-tRNA biosynthesis ECO:0000037
not_recorded
KEGG pae00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.30.930.10:FF:000022 Phenylalanine--tRNA ligase beta subunit - - 487 689 3.2E-70
SMART SM00873 B3_4_2 IPR005146 B3/B4 tRNA-binding domain 211 384 2.1E-95
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 39 190 2.4E-48
FunFam G3DSA:3.50.40.10:FF:000001 Phenylalanine--tRNA ligase beta subunit - - 195 396 1.7E-82
PANTHER PTHR10947 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 IPR045060 Phenylalanine-tRNA ligase, class IIc, beta subunit 2 683 1.3E-74
SUPERFAMILY SSF46955 Putative DNA-binding domain IPR009061 Putative DNA-binding domain superfamily 403 475 8.33E-18
Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type 1 785 46.855408
Gene3D G3DSA:3.30.930.10 Bira Bifunctional Protein; Domain 2 IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 485 690 1.7E-68
CDD cd00769 PheRS_beta_core IPR041616 Phenylalanyl tRNA synthetase beta chain, core domain 506 683 4.51049E-67
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 39 153 3.3E-73
SMART SM00874 B5_2 IPR005147 tRNA synthetase, B5-domain 402 471 1.8E-27
Gene3D G3DSA:3.30.70.380 - IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily 699 792 7.7E-28
SUPERFAMILY SSF56037 PheT/TilS domain - - 195 394 1.8E-74
FunFam G3DSA:2.40.50.140:FF:000045 Phenylalanine--tRNA ligase beta subunit - - 39 153 8.6E-47
NCBIfam TIGR00472 JCVI: phenylalanine--tRNA ligase subunit beta IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type 1 791 0.0
CDD cd02796 tRNA_bind_bactPheRS IPR033714 Phenylalanly tRNA synthetase, tRNA-binding-domain 45 146 8.81811E-51
Gene3D G3DSA:3.30.56.10 - - - 6 181 3.3E-73
Gene3D G3DSA:3.30.56.10 - - - 400 475 1.6E-22
FunFam G3DSA:3.30.56.10:FF:000002 Phenylalanine--tRNA ligase beta subunit - - 401 475 6.4E-23
Pfam PF17759 Phenylalanyl tRNA synthetase beta chain CLM domain IPR041616 Phenylalanyl tRNA synthetase beta chain, core domain 474 681 3.2E-61
Pfam PF01588 Putative tRNA binding domain IPR002547 tRNA-binding domain 45 144 1.2E-24
FunFam G3DSA:3.30.70.380:FF:000001 Phenylalanine--tRNA ligase beta subunit - - 699 792 5.9E-33
Gene3D G3DSA:3.50.40.10 - IPR020825 Phenylalanyl-tRNA synthetase-like, B3/B4 196 394 3.6E-80
Pfam PF03483 B3/4 domain IPR005146 B3/B4 tRNA-binding domain 211 383 1.5E-70
SMART SM00896 FDX_ACB_2 IPR005121 Ferrodoxin-fold anticodon-binding domain 698 791 1.9E-46
SUPERFAMILY SSF55681 Class II aaRS and biotin synthetases IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 467 683 8.45E-54
Pfam PF03484 tRNA synthetase B5 domain IPR005147 tRNA synthetase, B5-domain 405 471 1.3E-19
Pfam PF03147 Ferredoxin-fold anticodon binding domain IPR005121 Ferrodoxin-fold anticodon-binding domain 698 791 1.2E-30
SUPERFAMILY SSF54991 Anticodon-binding domain of PheRS IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily 692 791 2.09E-32

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.