Pseudomonas aeruginosa PAO1, PA2740 (pheS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009094 L-phenylalanine biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0044267 cellular protein metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0000162 tryptophan biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006571 tyrosine biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0043039 tRNA aminoacylation
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004818 glutamate-tRNA ligase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00468
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006432 phenylalanyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00468
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01409
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000049 tRNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01409
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00468
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0043039 tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01409
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00468
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004826 phenylalanine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00468
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Aminoacyl-tRNA biosynthesis ECO:0000037
not_recorded
PseudoCyc TRNA-CHARGING-PWY tRNA charging 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Phenylalanine, tyrosine and tryptophan biosynthesis ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal 20 87 5.3E-27
SUPERFAMILY SSF46589 tRNA-binding arm IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm 13 99 2.51E-23
NCBIfam TIGR00468 JCVI: phenylalanine--tRNA ligase subunit alpha IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit 38 337 1.7E-106
PANTHER PTHR11538 PHENYLALANYL-TRNA SYNTHETASE - - 89 337 1.2E-30
SUPERFAMILY SSF55681 Class II aaRS and biotin synthetases IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 92 338 2.68E-82
Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial 8 337 50.770996
CDD cd00496 PheRS_alpha_core - - 107 332 1.05767E-126
Gene3D G3DSA:3.30.930.10 Bira Bifunctional Protein; Domain 2 IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 7 338 0.0
FunFam G3DSA:3.30.930.10:FF:000003 Phenylalanine--tRNA ligase alpha subunit - - 8 338 0.0
Pfam PF01409 tRNA synthetases class II core domain (F) IPR002319 Phenylalanyl-tRNA synthetase 92 337 1.8E-108

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.