Pseudomonas aeruginosa PAO1, PA3195 (gapA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0044248 cellular catabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0015976 carbon utilization
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0006091 generation of precursor metabolites and energy
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00078
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006006 glucose metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01534
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00846
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050661 NADP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01534
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PAO1 genes in this class
Energy metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc ANAGLYCOLYSIS-PWY glycolysis III (from glucose) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc AERO-GLYCEROL-FERM-PWY aerobic glycerol degradation I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-5484 glycolysis II (from fructose 6-phosphate) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc GLYCOLYSIS-E-D superpathway of glycolysis and Entner-Doudoroff 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc GLYCOLYSIS+CITRIC-ACID-PWY glycolysis + citric acid pathway 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Glycolysis / Gluconeogenesis ECO:0000037
not_recorded
PseudoCyc P81-PWY glyceraldehyde 3-phosphate degradation 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc P461-PWY hexitol fermentation to lactate, formate, ethanol and acetate 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc P122-PWY heterolactic fermentation 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc GLYCOLYSIS glycolysis I (from glucose 6-phosphate) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00010 Glycolysis / Gluconeogenesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc GLUCONEO-PWY gluconeogenesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc GLYCOLYSIS-TCA-GLYOX-BYPASS superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.30.360.10:FF:000002 Glyceraldehyde-3-phosphate dehydrogenase - - 153 314 1.2E-70
Gene3D G3DSA:3.40.50.720 - - - 3 324 0.0
PIRSF PIRSF000149 GAPDH IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family 1 334 0.0
Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain 159 312 3.1E-61
PANTHER PTHR43148 GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE 2 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family 1 330 0.0
PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family 175 191 3.3E-35
PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family 112 125 3.3E-35
PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family 231 248 3.3E-35
Gene3D G3DSA:3.30.360.10 Dihydrodipicolinate Reductase; domain 2 - - 153 314 0.0
Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain 3 105 8.4E-38
SMART SM00846 gp_dh_n_7 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain 3 154 3.9E-92
PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family 269 284 3.3E-35
SUPERFAMILY SSF55347 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain - - 154 313 4.76E-67
NCBIfam TIGR01534 JCVI: glyceraldehyde-3-phosphate dehydrogenase, type I IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 9.3E-127
PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family 148 166 3.3E-35
FunFam G3DSA:3.40.50.720:FF:000001 Glyceraldehyde-3-phosphate dehydrogenase - - 3 162 3.1E-60
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 1 182 1.47E-61

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.