Pseudomonas aeruginosa PAO1, PA3975 (thiD)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0008817	cob(I)yrinic acid a,c-diamide adenosyltransferase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0051188	obsolete cofactor biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0009228	thiamine biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:cd01169	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008972	phosphomethylpyrimidine kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:cd01169	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCyc	PWY-6890	4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	THISYN-PWY	superpathway of thiamin diphosphate biosynthesis I	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00730	Thiamine metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
FunFam	G3DSA:3.40.1190.20:FF:000060	Phosphomethylpyrimidine kinase	-	-	1	259	0.0
Pfam	PF08543	Phosphomethylpyrimidine kinase	IPR013749	Pyridoxamine kinase/Phosphomethylpyrimidine kinase	17	253	1.5E-69
Gene3D	G3DSA:3.40.1190.20	-	IPR029056	Ribokinase-like	1	259	7.8E-78
SUPERFAMILY	SSF53613	Ribokinase-like	IPR029056	Ribokinase-like	6	255	1.18E-61
PANTHER	PTHR20858	PHOSPHOMETHYLPYRIMIDINE KINASE	-	-	7	255	3.1E-64
CDD	cd01169	HMPP_kinase	IPR004399	Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase domain	9	246	4.15037E-94

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.