Pseudomonas aeruginosa PAO1, PA3989 (holA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006259 DNA metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Cellular Component GO:0009360 DNA polymerase III complex
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 8505304 Reviewed by curator
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06144
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06144
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0009360 DNA polymerase III complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06144
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003887 DNA-directed DNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06144
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae03440 Homologous recombination 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae03030 DNA replication 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.40.50.300:FF:001131 DNA polymerase III subunit delta - - 1 136 1.1E-68
SUPERFAMILY SSF48019 post-AAA+ oligomerization domain-like IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal 213 337 3.57E-32
Gene3D G3DSA:1.10.8.60 - - - 145 213 2.4E-27
Pfam PF06144 DNA polymerase III, delta subunit IPR010372 DNA polymerase III delta, N-terminal 20 191 4.5E-32
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 1 138 7.4E-47
NCBIfam TIGR01128 JCVI: DNA polymerase III subunit delta IPR005790 DNA polymerase III, delta subunit 16 336 1.4E-110
FunFam G3DSA:1.10.8.60:FF:000085 DNA polymerase III subunit delta - - 145 213 6.2E-37
CDD cd18138 HLD_clamp_pol_III_delta - - 143 207 9.62372E-27
PANTHER PTHR34388 DNA POLYMERASE III SUBUNIT DELTA - - 1 338 1.3E-98
Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term IPR032780 DNA polymerase III subunit delta, C-terminal 216 339 8.6E-14
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 1 211 3.54E-49
Gene3D G3DSA:1.20.272.10 - - - 216 341 2.1E-36

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.