Pseudomonas aeruginosa PAO1, PA4376 (pncB2)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0051188	obsolete cofactor biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Molecular Function	GO:0004516	nicotinate phosphoribosyltransferase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	2211655	Reviewed by curator
Biological Process	GO:0009435	NAD biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:cd01401	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0004516	nicotinate phosphoribosyltransferase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:cd01401	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Nicotinate and nicotinamide metabolism		ECO:0000037 not_recorded
PseudoCyc	PYRNUCYC-PWY	pyridine nucleotide cycling	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00760	Nicotinate and nicotinamide metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Hamap	MF_00570	Nicotinate phosphoribosyltransferase [pncB].	IPR006406	Nicotinate phosphoribosyltransferase	7	398	48.512337
SUPERFAMILY	SSF51690	Nicotinate/Quinolinate PRTase C-terminal domain-like	IPR036068	Nicotinate phosphoribosyltransferase-like, C-terminal	122	396	3.2E-89
Pfam	PF04095	Nicotinate phosphoribosyltransferase (NAPRTase) family	IPR041525	Nicotinate/nicotinamide phosphoribosyltransferase	171	397	7.4E-69
SUPERFAMILY	SSF54675	Nicotinate/Quinolinate PRTase N-terminal domain-like	-	-	6	140	4.71E-42
FunFam	G3DSA:3.20.140.10:FF:000001	Nicotinate phosphoribosyltransferase	-	-	3	398	0.0
PIRSF	PIRSF000484	NAPRT	IPR007229	Nicotinate phosphoribosyltransferase family	1	385	5.6E-62
PANTHER	PTHR11098	NICOTINATE PHOSPHORIBOSYLTRANSFERASE	IPR007229	Nicotinate phosphoribosyltransferase family	8	389	4.8E-62
CDD	cd01401	PncB_like	IPR006406	Nicotinate phosphoribosyltransferase	12	380	0.0
NCBIfam	TIGR01514	JCVI: nicotinate phosphoribosyltransferase	IPR006406	Nicotinate phosphoribosyltransferase	10	397	0.0
Pfam	PF17767	Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain	IPR040727	Nicotinate phosphoribosyltransferase, N-terminal domain	15	132	6.8E-33
Gene3D	G3DSA:3.20.140.10	nicotinate phosphoribosyltransferase	-	-	4	398	0.0
Coils	Coil	Coil	-	-	142	162	-

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.