Pseudomonas aeruginosa PAO1, PA4561 (ribF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008531 riboflavin kinase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 9473052 Reviewed by curator
Molecular Function GO:0003919 FMN adenylyltransferase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 9473052 Reviewed by curator
Molecular Function GO:0003919 FMN adenylyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06574
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009231 riboflavin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06574
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008531 riboflavin kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF82114
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc RIBOSYN2-PWY flavin biosynthesis I (bacteria and plants) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00740 Riboflavin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Riboflavin metabolism ECO:0000037
not_recorded
PseudoCyc PWY-5523 5,6-dimethylbenzimidazole biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc P381-PWY adenosylcobalamin biosynthesis II (late cobalt incorporation) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR22749 RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE IPR023468 Riboflavin kinase 7 304 1.3E-48
Gene3D G3DSA:2.40.30.30 - IPR023465 Riboflavin kinase domain superfamily 186 309 2.2E-37
SUPERFAMILY SSF52374 Nucleotidylyl transferase - - 17 178 1.69E-31
Pfam PF06574 FAD synthetase IPR015864 FAD synthetase 15 167 1.0E-54
CDD cd02064 FAD_synthetase_N IPR015864 FAD synthetase 17 197 1.47763E-85
SMART SM00904 Flavokinase_2 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic 183 307 8.6E-60
NCBIfam TIGR00083 JCVI: riboflavin biosynthesis protein RibF IPR002606 Riboflavin kinase, bacterial 20 305 1.2E-96
PIRSF PIRSF004491 RibF_RibC IPR002606 Riboflavin kinase, bacterial 1 310 1.2E-103
FunFam G3DSA:3.40.50.620:FF:000021 Riboflavin biosynthesis protein - - 1 185 6.1E-66
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 1 185 1.1E-62
SUPERFAMILY SSF82114 Riboflavin kinase-like IPR023465 Riboflavin kinase domain superfamily 174 306 1.46E-43
Pfam PF01687 Riboflavin kinase IPR015865 Riboflavin kinase domain, bacterial/eukaryotic 184 305 9.3E-37

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.