Pseudomonas aeruginosa PAO1, PA4585 (rtcA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0005524	ATP binding	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	22167800	Reviewed by curator
Molecular Function	GO:0003963	RNA-3'-phosphate cyclase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	9738023	Reviewed by curator
Molecular Function	GO:0070566	adenylyltransferase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	21098490	Reviewed by curator
Biological Process	GO:0016070	RNA metabolic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Molecular Function	GO:0003824	catalytic activity	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF55205	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003963	RNA-3'-phosphate cyclase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR03399	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006396	RNA processing	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR03399	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcription, RNA processing and degradation Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PANTHER	PTHR11096	RNA 3' TERMINAL PHOSPHATE CYCLASE	IPR000228	RNA 3'-terminal phosphate cyclase	6	324	3.2E-67
FunFam	G3DSA:3.30.360.20:FF:000003	RNA 3'-terminal phosphate cyclase	-	-	183	275	3.0E-37
Hamap	MF_00200	RNA 3'-terminal phosphate cyclase [rtcA].	IPR017770	RNA 3'-terminal phosphate cyclase type 1	5	338	38.761127
SUPERFAMILY	SSF55205	EPT/RTPC-like	IPR013792	RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta	271	331	9.15E-7
Pfam	PF01137	RNA 3'-terminal phosphate cyclase	IPR023797	RNA 3'-terminal phosphate cyclase domain	12	324	1.9E-77
SUPERFAMILY	SSF52913	RNA 3'-terminal phosphate cyclase, RPTC, insert domain	IPR036553	RNA 3'-terminal phosphate cyclase, insert domain superfamily	184	278	3.92E-24
CDD	cd00874	RNA_Cyclase_Class_II	-	-	6	324	0.0
SUPERFAMILY	SSF55205	EPT/RTPC-like	IPR013792	RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta	5	175	1.77E-58
PIRSF	PIRSF005378	RNA_3-term_P_cyclase	IPR000228	RNA 3'-terminal phosphate cyclase	2	339	2.0E-97
Pfam	PF05189	RNA 3'-terminal phosphate cyclase (RTC), insert domain	IPR013791	RNA 3'-terminal phosphate cyclase, insert domain	183	272	1.7E-8
NCBIfam	TIGR03399	JCVI: RNA 3'-terminal-phosphate cyclase	IPR017770	RNA 3'-terminal phosphate cyclase type 1	6	324	5.2E-126
Gene3D	G3DSA:3.30.360.20	-	IPR036553	RNA 3'-terminal phosphate cyclase, insert domain superfamily	183	275	1.8E-114
Gene3D	G3DSA:3.65.10.20	-	IPR037136	RNA 3'-terminal phosphate cyclase domain superfamily	6	324	1.8E-114

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.