Pseudomonas aeruginosa PAO1, PA4930 (alr)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004418 hydroxymethylbilane synthase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0008784 alanine racemase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 20971724 Reviewed by curator
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0008784 alanine racemase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01201
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:2.40.37.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006522 alanine metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01201
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc anaerobic energy metabolism (invertebrates, cytosol) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae01502 Vancomycin resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Alanine and Aspartate metabolism ECO:0000037
not_recorded
PseudoCAP D-Alanine metabolism ECO:0000037
not_recorded
MetaCyc ansatrienin biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae00473 D-Alanine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR30511 ALANINE RACEMASE - - 1 357 1.4E-112
SUPERFAMILY SSF50621 Alanine racemase C-terminal domain-like IPR009006 Alanine racemase/group IV decarboxylase, C-terminal 227 357 9.77E-47
CDD cd06827 PLPDE_III_AR_proteobact - - 3 356 0.0
SMART SM01005 Ala_racemase_C_2 IPR011079 Alanine racemase, C-terminal 233 357 7.2E-66
NCBIfam TIGR00492 JCVI: alanine racemase IPR000821 Alanine racemase 4 356 1.1E-103
FunFam G3DSA:3.20.20.10:FF:000002 Alanine racemase - - 10 215 3.0E-61
PRINTS PR00992 Alanine racemase signature IPR000821 Alanine racemase 121 133 1.0E-62
PRINTS PR00992 Alanine racemase signature IPR000821 Alanine racemase 266 281 1.0E-62
Pfam PF01168 Alanine racemase, N-terminal domain IPR001608 Alanine racemase, N-terminal 8 219 5.1E-61
PRINTS PR00992 Alanine racemase signature IPR000821 Alanine racemase 287 304 1.0E-62
Pfam PF00842 Alanine racemase, C-terminal domain IPR011079 Alanine racemase, C-terminal 233 356 1.0E-41
Gene3D G3DSA:3.20.20.10 Alanine racemase IPR029066 PLP-binding barrel 10 212 7.0E-67
PRINTS PR00992 Alanine racemase signature IPR000821 Alanine racemase 26 42 1.0E-62
SUPERFAMILY SSF51419 PLP-binding barrel IPR029066 PLP-binding barrel 8 234 1.44E-69
PRINTS PR00992 Alanine racemase signature IPR000821 Alanine racemase 339 352 1.0E-62
PRINTS PR00992 Alanine racemase signature IPR000821 Alanine racemase 155 166 1.0E-62
Gene3D G3DSA:2.40.37.10 Lyase, Ornithine Decarboxylase; Chain A, domain 1 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal 213 358 6.4E-55
PRINTS PR00992 Alanine racemase signature IPR000821 Alanine racemase 192 219 1.0E-62
PRINTS PR00992 Alanine racemase signature IPR000821 Alanine racemase 61 79 1.0E-62
PRINTS PR00992 Alanine racemase signature IPR000821 Alanine racemase 249 264 1.0E-62
FunFam G3DSA:2.40.37.10:FF:000002 Alanine racemase - - 213 358 5.3E-58
Hamap MF_01201 Alanine racemase. IPR000821 Alanine racemase 3 357 54.188721

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.