Pseudomonas aeruginosa PAO1, PA5036 (gltB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004355 glutamate synthase (NADPH) activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 4565085 Reviewed by curator
Biological Process GO:0006537 glutamate biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 4565085 Reviewed by curator
Biological Process GO:0006537 glutamate biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01645
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006807 nitrogen compound metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04898
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01645
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0015930 glutamate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01645
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:2.160.20.60
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc GLUTAMOLYSIS-PWY glutamate degradation III 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc AMMASSIM-PWY ammonia assimilation cycle III 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc GLUTSYN-PWY L-glutamate biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc GLUTAMINEFUM-PWY L-glutamine degradation II 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Glutamate metabolism ECO:0000037
not_recorded
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Nitrogen metabolism ECO:0000037
not_recorded
KEGG pae00910 Nitrogen metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 780 1199 0.0
Gene3D G3DSA:2.160.20.60 - IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily 1200 1468 1.3E-98
Pfam PF00310 Glutamine amidotransferases class-II IPR017932 Glutamine amidotransferase type 2 domain 15 428 0.0
CDD cd02808 GltS_FMN IPR002932 Glutamate synthase domain 795 1168 0.0
PANTHER PTHR11938 FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE - - 18 1466 0.0
SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases) IPR029055 Nucleophile aminohydrolases, N-terminal 15 432 0.0
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 437 779 8.7E-118
SUPERFAMILY SSF51395 FMN-linked oxidoreductases - - 445 1187 0.0
FunFam G3DSA:3.60.20.10:FF:000001 Glutamate synthase, large subunit - - 15 438 0.0
CDD cd00713 GltS - - 15 423 0.0
Gene3D G3DSA:3.60.20.10 Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 IPR029055 Nucleophile aminohydrolases, N-terminal 15 436 0.0
FunFam G3DSA:3.20.20.70:FF:000061 Glutamate synthase large subunit - - 783 1195 0.0
Pfam PF01645 Conserved region in glutamate synthase IPR002932 Glutamate synthase domain 792 1155 0.0
CDD cd00982 gltB_C IPR002489 Glutamate synthase, alpha subunit, C-terminal 1213 1465 2.43058E-125
Pfam PF01493 GXGXG motif IPR002489 Glutamate synthase, alpha subunit, C-terminal 1236 1422 2.0E-76
FunFam G3DSA:3.20.20.70:FF:000109 Glutamate synthase, large subunit - - 436 782 0.0
Pfam PF04898 Glutamate synthase central domain IPR006982 Glutamate synthase, central-N 458 736 1.7E-99
FunFam G3DSA:2.160.20.60:FF:000002 Glutamate synthase, large subunit - - 1199 1469 0.0
SUPERFAMILY SSF69336 Alpha subunit of glutamate synthase, C-terminal domain IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily 1212 1466 6.54E-87

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.