Pseudomonas aeruginosa PAO1, PA5278 (dapF)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0008837 | diaminopimelate epimerase activity |
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P0A6K1
|
ECO:0000250 sequence similarity evidence used in manual assertion |
2689171 | Reviewed by curator |
| Biological Process | GO:0009089 | lysine biosynthetic process via diaminopimelate |
Inferred from Sequence Model
Term mapped from: InterPro:MF_00197
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0008837 | diaminopimelate epimerase activity |
Inferred from Sequence Model
Term mapped from: InterPro:MF_00197
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | pae01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae01130 | Biosynthesis of antibiotics | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| PseudoCyc | DAPLYSINESYN-PWY | L-lysine biosynthesis I | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| KEGG | pae01230 | Biosynthesis of amino acids | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae01120 | Microbial metabolism in diverse environments | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae01110 | Biosynthesis of secondary metabolites | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae00300 | Lysine biosynthesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| PseudoCAP | Lysine biosynthesis |
ECO:0000037
not_recorded |
|||
| PseudoCyc | P4-PWY | superpathway of L-lysine, L-threonine and L-methionine biosynthesis I | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Gene3D | G3DSA:3.10.310.10 | Diaminopimelate Epimerase; Chain A, domain 1 | - | - | 117 | 263 | 3.4E-105 |
| SUPERFAMILY | SSF54506 | Diaminopimelate epimerase-like | - | - | 3 | 276 | 3.77E-52 |
| Pfam | PF01678 | Diaminopimelate epimerase | IPR001653 | Diaminopimelate epimerase, DapF | 5 | 125 | 4.0E-33 |
| Gene3D | G3DSA:3.10.310.10 | Diaminopimelate Epimerase; Chain A, domain 1 | - | - | 4 | 272 | 3.4E-105 |
| NCBIfam | TIGR00652 | JCVI: diaminopimelate epimerase | IPR001653 | Diaminopimelate epimerase, DapF | 4 | 274 | 5.9E-90 |
| FunFam | G3DSA:3.10.310.10:FF:000001 | Diaminopimelate epimerase | - | - | 4 | 120 | 5.0E-50 |
| FunFam | G3DSA:3.10.310.10:FF:000002 | Diaminopimelate epimerase | - | - | 121 | 263 | 4.9E-69 |
| Pfam | PF01678 | Diaminopimelate epimerase | IPR001653 | Diaminopimelate epimerase, DapF | 154 | 269 | 5.7E-27 |
| PANTHER | PTHR31689 | DIAMINOPIMELATE EPIMERASE, CHLOROPLASTIC | IPR001653 | Diaminopimelate epimerase, DapF | 3 | 275 | 2.6E-108 |
| Hamap | MF_00197 | Diaminopimelate epimerase [dapF]. | IPR001653 | Diaminopimelate epimerase, DapF | 3 | 276 | 39.122734 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.