Pseudomonas aeruginosa PAO1, PA5336 (gmk)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009117 nucleotide metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004789 thiamine-phosphate diphosphorylase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006163 purine nucleotide metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00328
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004385 guanylate kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00328
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc PWY-7221 guanosine ribonucleotides de novo biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Purine metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR03263 JCVI: guanylate kinase IPR017665 Guanylate kinase 3 181 3.6E-74
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 5 180 7.2E-68
Pfam PF00625 Guanylate kinase IPR008145 Guanylate kinase/L-type calcium channel beta subunit 4 182 3.8E-54
Gene3D G3DSA:3.30.63.10 Guanylate Kinase phosphate binding domain - - 34 93 7.2E-68
CDD cd00071 GMPK - - 5 177 3.58769E-69
SMART SM00072 gk_7 IPR008145 Guanylate kinase/L-type calcium channel beta subunit 2 184 9.5E-62
PANTHER PTHR23117 GUANYLATE KINASE-RELATED - - 5 191 2.5E-64
FunFam G3DSA:3.40.50.300:FF:000084 Guanylate kinase - - 81 180 1.2E-32
Hamap MF_00328 Guanylate kinase [gmk]. IPR017665 Guanylate kinase 1 184 36.599079
FunFam G3DSA:3.30.63.10:FF:000002 Guanylate kinase 1 - - 34 93 7.4E-27
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 3 186 1.63E-70

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.