Pseudomonas aeruginosa PAO1, PA1512 (hcpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA1512
Name
hcpA
Replicon chromosome
Genomic location 1644207 - 1644725 (- strand)
Transposon Mutants in orthologs 7 transposon mutants in orthologs

Cross-References

RefSeq NP_250203.1
GI 15596709
DNASU PaCD00006692
Entrez 883081
GenBank AAG04901.1
NCBI Locus Tag PA1512
protein_id(GenBank) gb|AAG04901.1|AE004580_1|gnl|PseudoCAP|PA1512
TIGR NTL03PA01513
UniProtKB Acc Q9HI36
UniProtKB ID MAJE_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
secreted protein Hcp
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -5.88
Kyte-Doolittle Hydrophobicity Value -0.449
Molecular Weight (kDa) 19.1
Isoelectric Point (pI) 5.76

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3HE1 structural genomics, unknown function 05/07/09 Secreted protein Hcp3 from Pseudomonas aeruginosa. PSEUDOMONAS AERUGINOSA 2.098 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 67 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000260 (1018 members)
Putative Inparalogs 1 predicted inparalogs
secreted protein Hcp (PA0263) 100.0% identity

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1512
Search term: hcpA

References

Vibrio cholerae Hcp, a secreted protein coregulated with HlyA.
Williams SG, Varcoe LT, Attridge SR, Manning PA
Infect. Immun. 1996 Jan;64(1):283-9
PubMed ID: 8557353
Rhs elements comprise three subfamilies which diverged prior to acquisition by Escherichia coli.
Wang YD, Zhao S, Hill CW
J. Bacteriol. 1998 Aug;180(16):4102-10
PubMed ID: 9696756