Pseudomonas aeruginosa PAO1, PA3486 (vgrG4b)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA3486
Name
vgrG4b
Replicon chromosome
Genomic location 3900233 - 3902659 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 10 transposon mutants in orthologs

Cross-References

RefSeq NP_252176.1
GI 15598682
Affymetrix PA3486_at
Entrez 879939
GenBank AAG06874.1
INSDC AAG06874.1
NCBI Locus Tag PA3486
protein_id(GenBank) gb|AAG06874.1|AE004769_7|gnl|PseudoCAP|PA3486
TIGR NTL03PA03486
UniParc UPI00000C5A34
UniProtKB Acc Q9HYC3
UniProtKB ID Q9HYC3_PSEAE
UniRef100 UniRef100_Q9HYC3
UniRef50 UniRef50_Q9HYC3
UniRef90 UniRef90_Q9HYC3

Product

Feature Type CDS
Coding Frame 1
Product Name
VgrG4b
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -17.32
Kyte-Doolittle Hydrophobicity Value -0.584
Molecular Weight (kDa) 90.6
Isoelectric Point (pI) 6.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 152 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3404 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3486
Search term: vgrG4b
Search term: VgrG4b

References

Rhs elements comprise three subfamilies which diverged prior to acquisition by Escherichia coli.
Wang YD, Zhao S, Hill CW
J. Bacteriol. 1998 Aug;180(16):4102-10
PubMed ID: 9696756
Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins.
Hachani A, Lossi NS, Hamilton A, Jones C, Bleves S, Albesa-Jové D, Filloux A
J. Biol. Chem. 2011 Apr;286(14):12317-27
PubMed ID: 21325275