Pseudomonas aeruginosa UCBPP-PA14, PA14_18985 (vgrG4b)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_18985
Name
vgrG4b
Replicon chromosome
Genomic location 1638977 - 1641403 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 48 transposon mutants in orthologs

Cross-References

RefSeq YP_789661.1
GI 116054425
Entrez 4384198
INSDC ABJ15661.1
NCBI Locus Tag PA14_18985
UniParc UPI0000E44971
UniProtKB Acc Q02QX5
UniProtKB ID Q02QX5_PSEAB
UniRef100 UniRef100_Q02QX5
UniRef50 UniRef50_Q9HYC3
UniRef90 UniRef90_Q9HYC3

Product

Feature Type CDS
Coding Frame 1
Product Name
VgrG4b
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -16.80
Kyte-Doolittle Hydrophobicity Value -0.571
Molecular Weight (kDa) 90587.6
Isoelectric Point (pI) 6.23

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 151 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3427 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_18985
Search term: vgrG4b
Search term: VgrG4b

References

An rhs gene linked to the second type VI secretion cluster is a feature of the Pseudomonas aeruginosa strain PA14.
Jones C, Hachani A, Manoli E, Filloux A
J. Bacteriol. 2014 Feb;196(4):800-10
PubMed ID: 24317402
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A.
Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7707-7712.
PubMed ID: 28673999