Pseudomonas aeruginosa PAO1, PA1379

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1379
Name
Replicon chromosome
Genomic location 1496087 - 1496920 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250070.1
GI 15596576
Affymetrix PA1379_at
DNASU PaCD00006636
Entrez 881131
GenBank AAG04768.1
INSDC AAG04768.1
NCBI Locus Tag PA1379
protein_id(GenBank) gb|AAG04768.1|AE004567_7|gnl|PseudoCAP|PA1379
TIGR NTL03PA01380
UniParc UPI00000C5349
UniProtKB Acc Q9I3W5
UniProtKB ID Q9I3W5_PSEAE
UniRef100 UniRef100_W1MLB1
UniRef50 UniRef50_A9ALU7
UniRef90 UniRef90_W1MLB1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable short-chain dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -1.06
Kyte-Doolittle Hydrophobicity Value -0.079
Molecular Weight (kDa) 29.7
Isoelectric Point (pI) 6.54

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001308 (593 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1379

Human Homologs

Ensembl 110, assembly GRCh38.p14
retinol dehydrogenase 8 [Source:HGNC Symbol;Acc:HGNC:14423]
E-value: 1.5e-26
Percent Identity: 34.6
Ensembl 110, assembly GRCh38.p14
retinol dehydrogenase 8 [Source:HGNC Symbol;Acc:HGNC:14423]
E-value: 1.5e-26
Percent Identity: 34.6

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295