Pseudomonas aeruginosa PAO1, PA1776 (sigX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1776
Name
sigX
Replicon chromosome
Genomic location 1920568 - 1921065 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_250467.1
GI 15596973
Affymetrix PA1776_at
DNASU PaCD00006810
Entrez 878527
GenBank AAG05165.1
INSDC AAG05165.1
NCBI Locus Tag PA1776
protein_id(GenBank) gb|AAG05165.1|AE004603_5|gnl|PseudoCAP|PA1776
TIGR NTL03PA01777
UniParc UPI00000C5490
UniProtKB Acc Q9I2W5
UniProtKB ID Q9I2W5_PSEAE
UniRef100 UniRef100_W0YMY6
UniRef50 UniRef50_A4VL64
UniRef90 UniRef90_A4VL64

Product

Feature Type CDS
Coding Frame 1
Product Name
ECF sigma factor SigX
Product Name Confidence: Class 1
Synonyms ECF sigma factor, SigX
Evidence for Translation
Charge (pH 7) 2.39
Kyte-Doolittle Hydrophobicity Value -0.651
Molecular Weight (kDa) 19.7
Isoelectric Point (pI) 8.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 473 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003619 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1776
Search term: sigX

Human Homologs

References

Influence of a putative ECF sigma factor on expression of the major outer membrane protein, OprF, in Pseudomonas aeruginosa and Pseudomonas fluorescens.
Brinkman FS, Schoofs G, Hancock RE, De Mot R
J Bacteriol 1999 Aug;181(16):4746-54
PubMed ID: 10438740