Pseudomonas aeruginosa PAO1, PA2962 (tmk)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008834 di-trans,poly-cis-decaprenylcistransferase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0009117 nucleotide metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006233 dTDP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00041
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004798 thymidylate kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00041
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00041
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY0-166 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc PWY-7187 pyrimidine deoxyribonucleotides de novo biosynthesis II 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR10344 THYMIDYLATE KINASE - - 3 201 1.7E-27
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 1 207 4.13E-54
CDD cd01672 TMPK - - 4 201 5.17588E-90
Pfam PF02223 Thymidylate kinase IPR039430 Thymidylate kinase-like domain 8 195 4.0E-48
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 1 210 1.5E-71
FunFam G3DSA:3.40.50.300:FF:000321 Thymidylate kinase - - 1 210 2.1E-93
Hamap MF_00165 Thymidylate kinase [tmk]. IPR018094 Thymidylate kinase 4 205 30.132469
NCBIfam TIGR00041 JCVI: dTMP kinase IPR018094 Thymidylate kinase 2 195 5.8E-52

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.