Pseudomonas aeruginosa PAO1, PA3547 (algL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0042121 alginic acid biosynthetic process
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 8550492 Reviewed by curator
Molecular Function GO:0004794 L-threonine ammonia-lyase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 8370530 Reviewed by curator
Biological Process GO:0042122 alginic acid catabolic process
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 8370530 Reviewed by curator
Biological Process GO:0050896 response to stimulus
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 8370530 Reviewed by curator
Biological Process GO:0042122 alginic acid catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00557
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0042597 periplasmic space
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF05426
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016829 lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF05426
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0045135 poly(beta-D-mannuronate) lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00557
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Secreted Factors (toxins, enzymes, alginate) Other PAO1 genes in this class
Adaptation, Protection Other PAO1 genes in this class
Cell wall / LPS / capsule Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Alginate biosynthesis ECO:0000037
not_recorded
PseudoCyc PWY-6082 alginate biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00051 Fructose and mannose metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00244 AlgLyase IPR022859 Alginate lyase 24 361 0.0
FunFam G3DSA:1.50.10.100:FF:000002 Alginate lyase - - 28 362 0.0
Hamap MF_00557 Alginate lyase [algL]. IPR022859 Alginate lyase 5 367 55.739719
SUPERFAMILY SSF48230 Chondroitin AC/alginate lyase IPR008929 Chondroitin AC/alginate lyase 30 361 1.46E-62
Gene3D G3DSA:1.50.10.100 Chondroitin AC/alginate lyase IPR008929 Chondroitin AC/alginate lyase 28 362 0.0
Pfam PF05426 Alginate lyase IPR008397 Alginate lyase domain 63 303 7.8E-59

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.