Pseudomonas aeruginosa PAO1, PA5015 (aceE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006520 cellular amino acid metabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0008836 diaminopimelate decarboxylase activity
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0006091 generation of precursor metabolites and energy
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF52922
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000156
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class
Energy metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00020 Citrate cycle (TCA cycle) 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Butanoate metabolism ECO:0000037
not_recorded
KEGG pae00620 Pyruvate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Pyruvate metabolism ECO:0000037
not_recorded
PseudoCAP Valine, leucine and isoleucine biosynthesis ECO:0000037
not_recorded
KEGG pae01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Glycolysis / Gluconeogenesis ECO:0000037
not_recorded
PseudoCyc LCTACACAT-PWY lactate oxidation 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00010 Glycolysis / Gluconeogenesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52922 TK C-terminal domain-like IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II 694 880 1.17E-63
Gene3D G3DSA:3.40.50.920 - IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II 699 881 2.7E-83
CDD cd02017 TPP_E1_EcPDC_like IPR035807 Pyruvate dehydrogenase E1 component, N-terminal 70 454 0.0
NCBIfam TIGR00759 JCVI: pyruvate dehydrogenase (acetyl-transferring), homodimeric type IPR004660 Pyruvate dehydrogenase E1 component 2 880 0.0
PIRSF PIRSF000156 Pyruvate_dh_E1 IPR004660 Pyruvate dehydrogenase E1 component 1 882 0.0
FunFam G3DSA:3.40.50.970:FF:000011 Pyruvate dehydrogenase E1 component - - 51 464 0.0
Pfam PF17831 Pyruvate dehydrogenase E1 component middle domain IPR041621 Pyruvate dehydrogenase E1 component, middle domain 473 692 4.2E-117
Coils Coil Coil - - 880 882 -
Pfam PF00456 Transketolase, thiamine diphosphate binding domain IPR005474 Transketolase, N-terminal 123 287 4.6E-8
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 466 693 2.94E-97
Gene3D G3DSA:3.40.50.970 - - - 465 698 1.4E-113
PANTHER PTHR43825 PYRUVATE DEHYDROGENASE E1 COMPONENT - - 62 856 0.0
Gene3D G3DSA:3.40.50.970 - - - 51 464 0.0
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 52 460 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.