Pseudomonas aeruginosa PAO1, PA5045 (ponA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0009276 Gram-negative-bacterium-type cell wall
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0009273 peptidoglycan-based cell wall biogenesis
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 2211517 Reviewed by curator
Molecular Function GO:0016757 transferase activity, transferring glycosyl groups
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: CAZy:GT51
 ECO:0000250
sequence similarity evidence used in manual assertion		 18838391 Reviewed by curator
Molecular Function GO:0008658 penicillin binding
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 9358038 Reviewed by curator
Molecular Function GO:0008658 penicillin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00905
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Peptideglycan biosynthesis ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00550 Peptidoglycan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01501 beta-Lactam resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00905 Penicillin binding protein transpeptidase domain IPR001460 Penicillin-binding protein, transpeptidase 428 605 2.5E-24
MobiDBLite mobidb-lite consensus disorder prediction - - 614 654 -
PANTHER PTHR32282 BINDING PROTEIN TRANSPEPTIDASE, PUTATIVE-RELATED - - 3 800 0.0
Gene3D G3DSA:3.40.710.10 - IPR012338 Beta-lactamase/transpeptidase-like 400 621 2.4E-77
Pfam PF17092 Penicillin-binding protein OB-like domain IPR031376 Penicillin-binding protein, OB-like domain 316 420 6.0E-25
Pfam PF00912 Transglycosylase IPR001264 Glycosyl transferase, family 51 55 229 2.1E-65
FunFam G3DSA:1.10.3810.10:FF:000003 Penicillin-binding protein 1a - - 48 242 1.4E-82
FunFam G3DSA:3.40.710.10:FF:000042 Penicillin-binding protein 1A - - 243 329 1.6E-37
NCBIfam TIGR02074 JCVI: PBP1A family penicillin-binding protein - - 65 751 0.0
Gene3D G3DSA:3.40.710.10 - IPR012338 Beta-lactamase/transpeptidase-like 243 323 6.7E-11
Gene3D G3DSA:1.10.3810.10 - IPR036950 Penicillin binding protein transglycosylase domain 48 242 1.5E-76
SUPERFAMILY SSF53955 Lysozyme-like IPR023346 Lysozyme-like domain superfamily 43 255 9.84E-78
MobiDBLite mobidb-lite consensus disorder prediction - - 790 822 -
Pfam PF00905 Penicillin binding protein transpeptidase domain IPR001460 Penicillin-binding protein, transpeptidase 648 741 3.4E-6
Gene3D G3DSA:3.40.710.10 - IPR012338 Beta-lactamase/transpeptidase-like 631 792 7.5E-60
SUPERFAMILY SSF56601 beta-lactamase/transpeptidase-like IPR012338 Beta-lactamase/transpeptidase-like 211 801 4.13E-130

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.