Pseudomonas fluorescens Pf0-1, Pfl01_0462 (aceF)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0004742 | dihydrolipoyllysine-residue acetyltransferase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0045254 | pyruvate dehydrogenase complex |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0016746 | transferase activity, transferring acyl groups |
Inferred from Sequence Model
Term mapped from: InterPro:PF00198
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006096 | glycolytic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
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Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | pfo00020 | Citrate cycle (TCA cycle) | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pfo00010 | Glycolysis / Gluconeogenesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pfo01200 | Carbon metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pfo01130 | Biosynthesis of antibiotics | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pfo00620 | Pyruvate metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pfo01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pfo01120 | Microbial metabolism in diverse environments | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pfo01110 | Biosynthesis of secondary metabolites | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| CDD | cd06849 | lipoyl_domain | - | - | 117 | 189 | 4.23339E-19 |
| Gene3D | G3DSA:2.40.50.100 | - | - | - | 227 | 304 | 1.6E-21 |
| FunFam | G3DSA:2.40.50.100:FF:000009 | Acetyltransferase component of pyruvate dehydrogenase complex | - | - | 1 | 80 | 5.2E-30 |
| NCBIfam | TIGR01348 | JCVI: dihydrolipoyllysine-residue acetyltransferase | IPR006256 | Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex | 205 | 651 | 0.0 |
| SUPERFAMILY | SSF52777 | CoA-dependent acyltransferases | - | - | 410 | 651 | 2.94E-81 |
| CDD | cd06849 | lipoyl_domain | - | - | 5 | 74 | 1.08254E-19 |
| Pfam | PF00364 | Biotin-requiring enzyme | IPR000089 | Biotin/lipoyl attachment | 5 | 74 | 5.9E-21 |
| FunFam | G3DSA:2.40.50.100:FF:000009 | Acetyltransferase component of pyruvate dehydrogenase complex | - | - | 225 | 305 | 1.1E-27 |
| Pfam | PF00198 | 2-oxoacid dehydrogenases acyltransferase (catalytic domain) | IPR001078 | 2-oxoacid dehydrogenase acyltransferase, catalytic domain | 422 | 650 | 1.6E-77 |
| SUPERFAMILY | SSF51230 | Single hybrid motif | IPR011053 | Single hybrid motif | 4 | 93 | 1.57E-22 |
| Gene3D | G3DSA:2.40.50.100 | - | - | - | 116 | 195 | 1.3E-21 |
| Pfam | PF02817 | e3 binding domain | IPR004167 | Peripheral subunit-binding domain | 348 | 383 | 3.2E-14 |
| SUPERFAMILY | SSF51230 | Single hybrid motif | IPR011053 | Single hybrid motif | 116 | 209 | 9.16E-23 |
| Gene3D | G3DSA:3.30.559.10 | - | IPR023213 | Chloramphenicol acetyltransferase-like domain superfamily | 409 | 651 | 3.7E-87 |
| PANTHER | PTHR43178 | DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX | - | - | 113 | 219 | 0.0 |
| Gene3D | G3DSA:4.10.320.10 | - | IPR036625 | E3-binding domain superfamily | 336 | 388 | 1.9E-17 |
| FunFam | G3DSA:3.30.559.10:FF:000004 | Acetyltransferase component of pyruvate dehydrogenase complex | - | - | 406 | 651 | 2.5E-118 |
| SUPERFAMILY | SSF47005 | Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | IPR036625 | E3-binding domain superfamily | 342 | 387 | 4.05E-12 |
| CDD | cd06849 | lipoyl_domain | - | - | 227 | 299 | 1.93514E-18 |
| FunFam | G3DSA:2.40.50.100:FF:000009 | Acetyltransferase component of pyruvate dehydrogenase complex | - | - | 115 | 195 | 1.2E-28 |
| Pfam | PF00364 | Biotin-requiring enzyme | IPR000089 | Biotin/lipoyl attachment | 228 | 299 | 7.1E-22 |
| SUPERFAMILY | SSF51230 | Single hybrid motif | IPR011053 | Single hybrid motif | 226 | 319 | 4.45E-22 |
| Gene3D | G3DSA:2.40.50.100 | - | - | - | 2 | 80 | 1.8E-23 |
| Pfam | PF00364 | Biotin-requiring enzyme | IPR000089 | Biotin/lipoyl attachment | 118 | 188 | 1.3E-21 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.