Pseudomonas fluorescens F113, PSF113_0561 (mutL)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0140664	ATP-dependent DNA damage sensor activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR10073	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Cellular Component	GO:0032300	mismatch repair complex	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR10073	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016887	ATPase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR10073	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF01119	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006298	mismatch repair	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00149	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0030983	mismatched DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF01119	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pfe03430	Mismatch repair	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Hamap	MF_00149	DNA mismatch repair protein MutL [mutL].	IPR020667	DNA mismatch repair protein, MutL	10	633	29.786922
MobiDBLite	mobidb-lite	consensus disorder prediction	-	-	384	412	-
SUPERFAMILY	SSF118116	DNA mismatch repair protein MutL	IPR037198	MutL, C-terminal domain superfamily	446	635	1.83E-60
FunFam	G3DSA:3.30.565.10:FF:000003	DNA mismatch repair endonuclease MutL	-	-	10	220	2.3E-84
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	10	212	2.36E-54
FunFam	G3DSA:3.30.230.10:FF:000013	DNA mismatch repair endonuclease MutL	-	-	226	337	2.7E-53
NCBIfam	TIGR00585	JCVI: DNA mismatch repair endonuclease MutL	IPR002099	DNA mismatch repair protein MutL/Mlh/PMS	12	562	0.0
Gene3D	G3DSA:3.30.1370.100	-	IPR042121	MutL, C-terminal domain, regulatory subdomain	493	588	2.1E-57
PANTHER	PTHR10073	DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL	IPR038973	DNA mismatch repair protein MutL/Mlh/Pms-like	452	624	6.8E-124
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	11	225	5.9E-71
Pfam	PF13589	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	33	135	2.9E-11
Pfam	PF08676	MutL C terminal dimerisation domain	IPR014790	MutL, C-terminal, dimerisation	446	593	5.3E-50
FunFam	G3DSA:3.30.1370.100:FF:000005	DNA mismatch repair protein MutL	-	-	493	588	1.6E-48
SMART	SM00853	MutL_C_2	IPR014790	MutL, C-terminal, dimerisation	450	593	3.1E-55
SMART	SM01340	DNA_mis_repair_2	IPR013507	DNA mismatch repair protein, S5 domain 2-like	221	339	2.8E-61
Gene3D	G3DSA:3.30.230.10	-	IPR014721	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	226	336	4.8E-31
CDD	cd03482	MutL_Trans_MutL	-	-	217	338	1.19588E-70
Pfam	PF01119	DNA mismatch repair protein, C-terminal domain	IPR013507	DNA mismatch repair protein, S5 domain 2-like	223	338	6.3E-39
CDD	cd16926	HATPase_MutL-MLH-PMS-like	-	-	19	206	1.29539E-108
SUPERFAMILY	SSF54211	Ribosomal protein S5 domain 2-like	IPR020568	Ribosomal protein uS5 domain 2-type superfamily	200	339	6.07E-40
Gene3D	G3DSA:3.30.1540.20	-	IPR042120	MutL, C-terminal domain, dimerisation subdomain	453	630	2.1E-57

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.