Pseudomonas fluorescens F113, PSF113_4616 (ruvA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003678 DNA helicase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00031
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07499
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0009378 four-way junction helicase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07499
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006310 DNA recombination
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07499
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0009379 Holliday junction helicase complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07499
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07499
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pfe03440 Homologous recombination 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:1.10.8.10 - - - 157 202 2.3E-18
Hamap MF_00031 Holliday junction branch migration complex subunit RuvA [ruvA]. IPR000085 Holliday junction branch migration complex subunit RuvA 1 202 31.586987
CDD cd14332 UBA_RuvA_C IPR011114 Holliday junction DNA helicase RuvA, C-terminal 157 199 2.61311E-12
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 108 127 0.0055
NCBIfam TIGR00084 JCVI: Holliday junction branch migration protein RuvA IPR000085 Holliday junction branch migration complex subunit RuvA 1 200 3.7E-60
Pfam PF07499 RuvA, C-terminal domain IPR011114 Holliday junction DNA helicase RuvA, C-terminal 158 201 3.0E-16
SUPERFAMILY SSF46929 DNA helicase RuvA subunit, C-terminal domain IPR036267 RuvA, C-terminal domain superfamily 158 201 5.23E-11
Pfam PF01330 RuvA N terminal domain IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial 1 62 4.7E-22
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 1 64 6.8E-26
Pfam PF14520 Helix-hairpin-helix domain - - 72 130 8.9E-18
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 73 92 0.2
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 66 136 1.11E-22
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 1 63 2.23E-18
Gene3D G3DSA:1.10.150.20 - - - 67 139 2.4E-29

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.