Pseudomonas fluorescens SBW25, PFLU0459 (aceF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016746 transferase activity, transferring acyl groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00198
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0045254 pyruvate dehydrogenase complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006096 glycolytic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004742 dihydrolipoyllysine-residue acetyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00620 Pyruvate metabolism InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion 		0
KEGG (InterPro) 00010 Glycolysis / Gluconeogenesis InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion 		0
KEGG (InterPro) 00020 Citrate cycle (TCA cycle) InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion 		0

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00364 Biotin-requiring enzyme IPR000089 Biotin/lipoyl attachment 122 193 1.1E-21
FunFam G3DSA:2.40.50.100:FF:000009 Acetyltransferase component of pyruvate dehydrogenase complex - - 119 199 5.7E-28
Pfam PF00364 Biotin-requiring enzyme IPR000089 Biotin/lipoyl attachment 5 74 9.9E-22
Gene3D G3DSA:3.30.559.10 - IPR023213 Chloramphenicol acetyltransferase-like domain superfamily 308 549 4.1E-88
FunFam G3DSA:3.30.559.10:FF:000004 Acetyltransferase component of pyruvate dehydrogenase complex - - 304 549 1.2E-118
PANTHER PTHR43178 DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX - - 5 115 0.0
NCBIfam TIGR01348 JCVI: dihydrolipoyllysine-residue acetyltransferase IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex 103 549 0.0
CDD cd06849 lipoyl_domain - - 5 74 4.89873E-21
SUPERFAMILY SSF51230 Single hybrid motif IPR011053 Single hybrid motif 120 213 1.16E-22
SUPERFAMILY SSF47005 Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex IPR036625 E3-binding domain superfamily 241 286 3.14E-12
CDD cd06849 lipoyl_domain - - 121 193 1.52304E-19
SUPERFAMILY SSF52777 CoA-dependent acyltransferases - - 308 549 2.18E-81
FunFam G3DSA:2.40.50.100:FF:000009 Acetyltransferase component of pyruvate dehydrogenase complex - - 1 80 2.3E-30
Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain 320 548 1.4E-78
Pfam PF02817 e3 binding domain IPR004167 Peripheral subunit-binding domain 247 282 1.2E-14
Gene3D G3DSA:2.40.50.100 - - - 121 198 2.8E-21
Gene3D G3DSA:4.10.320.10 - IPR036625 E3-binding domain superfamily 235 287 4.0E-17
Gene3D G3DSA:2.40.50.100 - - - 2 79 9.9E-24
SUPERFAMILY SSF51230 Single hybrid motif IPR011053 Single hybrid motif 4 94 4.45E-23

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.