Pseudomonas fluorescens SBW25, PFLU5615 (bioB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004076 biotin synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR22976
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00729
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009102 biotin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR22976
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00729
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00780 Biotin metabolism InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion 		0
UniPathway UPA00078 biotin biosynthesis InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion 		0

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF04055 Radical SAM superfamily IPR007197 Radical SAM 56 211 1.7E-12
Pfam PF06968 Biotin and Thiamin Synthesis associated domain IPR010722 Biotin and thiamin synthesis-associated domain 226 316 4.6E-19
SMART SM00729 MiaB IPR006638 Elp3/MiaA/NifB-like, radical SAM core domain 49 261 2.7E-36
FunFam G3DSA:3.20.20.70:FF:000011 Biotin synthase - - 10 321 0.0
SFLD SFLDG01060 BATS domain containing - - 4 325 0.0
SUPERFAMILY SSF102114 Radical SAM enzymes - - 11 318 2.22E-87
PANTHER PTHR22976 BIOTIN SYNTHASE IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 5 335 0.0
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 10 321 0.0
Hamap MF_01694 Biotin synthase [bioB]. IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 11 319 41.392723
NCBIfam TIGR00433 JCVI: biotin synthase BioB IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 12 316 1.8E-122
PIRSF PIRSF001619 Biotin_synth IPR024177 Biotin synthase 1 325 0.0
SMART SM00876 BATS_2 IPR010722 Biotin and thiamin synthesis-associated domain 226 318 7.3E-47
CDD cd01335 Radical_SAM - - 56 255 1.3888E-12
SFLD SFLDF00272 biotin synthase IPR024177 Biotin synthase 4 325 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.