Pseudomonas putida BIRD-1, PPUBIRD1_0151 (polA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00476
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006139 nucleobase-containing compound metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00474
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.420.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003887 DNA-directed DNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00593
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008408 3'-5' exonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00474
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006261 DNA-dependent DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR10133
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00593
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd09898
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG ppb00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG ppb00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG ppb03440 Homologous recombination 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG ppb03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG ppb03030 DNA replication 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG ppb01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG ppb03420 Nucleotide excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 832 848 8.5E-78
CDD cd08637 DNA_pol_A_pol_I_C - - 534 912 0.0
FunFam G3DSA:1.20.1060.10:FF:000001 DNA polymerase I - - 529 645 6.9E-39
Gene3D G3DSA:3.30.70.370 - - - 651 911 8.1E-114
PANTHER PTHR10133 DNA POLYMERASE I IPR002298 DNA polymerase A 316 915 0.0
SUPERFAMILY SSF88723 PIN domain-like IPR029060 PIN-like domain superfamily 5 167 4.77E-52
SUPERFAMILY SSF56672 DNA/RNA polymerases IPR043502 DNA/RNA polymerase superfamily 510 915 0.0
FunFam G3DSA:3.40.50.1010:FF:000001 DNA polymerase I - - 1 169 9.0E-70
Gene3D G3DSA:3.40.50.1010 - - - 1 169 4.3E-53
SMART SM00475 53exo3 IPR002421 5'-3' exonuclease 4 266 7.5E-115
FunFam G3DSA:1.10.150.20:FF:000002 DNA polymerase I - - 696 839 1.7E-59
Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold IPR020045 DNA polymerase I-like, H3TH domain 168 270 7.9E-28
Pfam PF00476 DNA polymerase family A IPR001098 DNA-directed DNA polymerase, family A, palm domain 536 913 0.0
CDD cd09859 PIN_53EXO - - 8 164 1.37193E-75
SMART SM00474 35exoneu6 IPR002562 3'-5' exonuclease domain 314 503 2.9E-36
Gene3D G3DSA:3.30.420.10 - IPR036397 Ribonuclease H superfamily 311 528 3.1E-73
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 717 730 8.5E-78
CDD cd09898 H3TH_53EXO IPR020045 DNA polymerase I-like, H3TH domain 170 250 6.58894E-23
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 687 710 8.5E-78
NCBIfam TIGR00593 JCVI: DNA polymerase I IPR018320 DNA polymerase 1 6 915 0.0
Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal 6 167 5.6E-50
Gene3D G3DSA:1.10.150.20 - - - 170 265 8.3E-26
SUPERFAMILY SSF47807 5' to 3' exonuclease, C-terminal subdomain IPR036279 5'-3' exonuclease, C-terminal domain superfamily 168 289 4.93E-30
SUPERFAMILY SSF53098 Ribonuclease H-like IPR012337 Ribonuclease H-like superfamily 311 503 4.18E-54
FunFam G3DSA:1.10.150.20:FF:000003 DNA polymerase I - - 170 266 2.6E-26
Pfam PF01612 3'-5' exonuclease IPR002562 3'-5' exonuclease domain 314 502 4.3E-38
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 741 766 8.5E-78
SMART SM00279 HhH_4 IPR008918 Helix-hairpin-helix motif, class 2 170 205 1.2E-12
FunFam G3DSA:3.30.420.10:FF:000026 DNA polymerase I - - 311 528 4.5E-98
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 642 664 8.5E-78
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 778 789 8.5E-78
CDD cd06139 DNA_polA_I_Ecoli_like_exo - - 329 525 7.31569E-95
Gene3D G3DSA:1.20.1060.10 Taq DNA Polymerase; Chain T, domain 4 - - 529 645 3.4E-35
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 800 811 8.5E-78
SMART SM00482 polaultra3 IPR001098 DNA-directed DNA polymerase, family A, palm domain 673 879 3.7E-117
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 665 680 8.5E-78
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 862 875 8.5E-78
Gene3D G3DSA:1.10.150.20 - - - 696 839 8.1E-114

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.