Pseudomonas aeruginosa PA7, PSPA7_4142 (aprI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008191 metalloendopeptidase inhibitor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01274
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004866 endopeptidase inhibitor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50882
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0010951 negative regulation of endopeptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01274
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Secreted Factors (toxins, enzymes, alginate) Other PA7 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01274 Metalloprotease inhibitor signature IPR022815 Protease inhibitor 67 80 9.1E-19
PRINTS PR01274 Metalloprotease inhibitor signature IPR022815 Protease inhibitor 3 19 9.1E-19
PRINTS PR01274 Metalloprotease inhibitor signature IPR022815 Protease inhibitor 84 97 9.1E-19
Pfam PF02974 Protease inhibitor Inh IPR021140 Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19 8 105 4.4E-23
PRINTS PR01274 Metalloprotease inhibitor signature IPR022815 Protease inhibitor 45 56 9.1E-19
Gene3D G3DSA:2.40.128.10 - - - 3 108 1.8E-33
SUPERFAMILY SSF50882 beta-Barrel protease inhibitors IPR016085 Protease inhibitor, beta-barrel domain 3 106 3.92E-27

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.