Pseudomonas aeruginosa M18, PAM18_1813

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0000271 polysaccharide biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA3159
 ECO:0000249
sequence similarity evidence used in automatic assertion		 15226302
Molecular Function GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR43491
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000271 polysaccharide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR43491
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03720
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000124
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other M18 genes in this class
Putative enzymes Other M18 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paf00520 Amino sugar and nucleotide sugar metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal 5 178 1.4E-34
PIRSF PIRSF000124 UDPglc_GDPman_dh IPR017476 UDP-glucose/GDP-mannose dehydrogenase 4 420 2.9E-52
Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation 200 288 5.6E-24
Gene3D G3DSA:3.40.50.720 - - - 198 420 1.2E-50
PIRSF PIRSF500136 UDP_ManNAc_DH IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase 1 422 0.0
SUPERFAMILY SSF48179 6-phosphogluconate dehydrogenase C-terminal domain-like IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 199 289 1.26E-24
SMART SM00984 UDPG_MGDP_dh_C_a_2_a IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal 315 415 4.9E-35
Gene3D G3DSA:3.40.50.720 - - - 1 196 1.9E-55
NCBIfam TIGR03026 JCVI: nucleotide sugar dehydrogenase IPR017476 UDP-glucose/GDP-mannose dehydrogenase 5 408 2.8E-120
SUPERFAMILY SSF52413 UDP-glucose/GDP-mannose dehydrogenase C-terminal domain IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily 298 415 1.11E-28
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 5 189 2.6E-46
PANTHER PTHR43491 UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase 3 418 0.0
Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal 316 414 6.2E-20

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.