Pseudomonas aeruginosa DK2, PADK2_00005 (dnaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00760
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00362
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00760
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006275 regulation of DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00760
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003688 DNA replication origin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00362
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006270 DNA replication initiation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00760
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other DK2 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdk02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:1.10.1750.10:FF:000001 Chromosomal replication initiator protein DnaA - - 288 381 1.4E-53
SUPERFAMILY SSF48295 TrpR-like IPR010921 Trp repressor/replication initiator 277 379 3.92E-36
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 79 99 5.4E-53
FunFam G3DSA:3.40.50.300:FF:000103 Chromosomal replication initiator protein DnaA - - 44 211 2.5E-100
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 111 125 5.4E-53
Pfam PF08299 Bacterial dnaA protein helix-turn-helix IPR013159 Chromosomal replication initiator, DnaA C-terminal 290 358 9.2E-31
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 339 358 5.4E-53
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 177 204 5.4E-53
NCBIfam TIGR00362 JCVI: chromosomal replication initiator protein DnaA IPR001957 Chromosomal replication control, initiator DnaA 33 379 0.0
PANTHER PTHR30050 CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA - - 38 371 0.0
Gene3D G3DSA:1.10.1750.10 - IPR010921 Trp repressor/replication initiator 288 381 1.7E-33
Pfam PF00308 Bacterial dnaA protein IPR013317 Chromosomal replication initiator protein DnaA 46 263 4.8E-100
FunFam G3DSA:1.10.8.60:FF:000003 Chromosomal replication initiator protein DnaA - - 212 282 1.5E-33
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 78 287 2.3E-7
Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. IPR001957 Chromosomal replication control, initiator DnaA 3 380 29.592197
SMART SM00760 bac_dnaa_c7seqb IPR013159 Chromosomal replication initiator, DnaA C-terminal 289 358 2.2E-41
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 45 211 6.2E-50
CDD cd00009 AAA - - 79 204 2.79043E-17
Gene3D G3DSA:1.10.8.60 - - - 212 282 3.9E-27
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 47 257 9.92E-45
CDD cd06571 Bac_DnaA_C IPR013159 Chromosomal replication initiator, DnaA C-terminal 290 379 7.24124E-31
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 143 157 5.4E-53

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.