Pseudomonas aeruginosa DK2, PADK2_00180 (trpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0000162 tryptophan biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA0035
 ECO:0000249
sequence similarity evidence used in automatic assertion		 3127651
Biological Process GO:0006568 tryptophan metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00290
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004834 tryptophan synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00290
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other DK2 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdk01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 1 268 1.9E-104
SUPERFAMILY SSF51366 Ribulose-phoshate binding barrel IPR011060 Ribulose-phosphate binding barrel 1 248 1.51E-92
NCBIfam TIGR00262 JCVI: tryptophan synthase subunit alpha IPR002028 Tryptophan synthase, alpha chain 8 259 3.2E-81
FunFam G3DSA:3.20.20.70:FF:000037 Tryptophan synthase alpha chain - - 1 266 4.4E-101
PANTHER PTHR43406 TRYPTOPHAN SYNTHASE, ALPHA CHAIN IPR002028 Tryptophan synthase, alpha chain 3 262 8.2E-85
Pfam PF00290 Tryptophan synthase alpha chain IPR002028 Tryptophan synthase, alpha chain 8 263 3.2E-106
CDD cd04724 Tryptophan_synthase_alpha IPR002028 Tryptophan synthase, alpha chain 18 260 2.07603E-121
Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. IPR002028 Tryptophan synthase, alpha chain 14 263 38.09428

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.