Pseudomonas aeruginosa DK2, PADK2_12990

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004375 glycine dehydrogenase (decarboxylating) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02347
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006544 glycine metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00711
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006546 glycine catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02347
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdk01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk00630 Glyoxylate and dicarboxylate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02347 Glycine cleavage system P-protein IPR020581 Glycine cleavage system P protein 21 444 0.0
PANTHER PTHR11773 GLYCINE DEHYDROGENASE, DECARBOXYLATING IPR020581 Glycine cleavage system P protein 13 956 0.0
Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase, domain 1 IPR015422 Pyridoxal phosphate-dependent transferase, small domain 88 415 4.9E-84
NCBIfam TIGR00461 JCVI: aminomethyl-transferring glycine dehydrogenase IPR003437 Glycine dehydrogenase (decarboxylating) 21 950 0.0
CDD cd00613 GDC-P IPR020581 Glycine cleavage system P protein 488 873 0.0
SUPERFAMILY SSF53383 PLP-dependent transferases IPR015424 Pyridoxal phosphate-dependent transferase 21 446 9.92E-99
Coils Coil Coil - - 635 655 -
Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. IPR003437 Glycine dehydrogenase (decarboxylating) 12 956 26.176762
FunFam G3DSA:3.40.640.10:FF:000005 Glycine dehydrogenase (decarboxylating), mitochondrial - - 99 359 0.0
FunFam G3DSA:3.40.640.10:FF:000007 glycine dehydrogenase (Decarboxylating), mitochondrial - - 527 758 5.3E-121
Gene3D G3DSA:3.40.640.10 - IPR015421 Pyridoxal phosphate-dependent transferase, major domain 99 359 4.9E-84
Gene3D G3DSA:3.40.640.10 - IPR015421 Pyridoxal phosphate-dependent transferase, major domain 528 769 1.8E-73
Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase, domain 1 IPR015422 Pyridoxal phosphate-dependent transferase, small domain 770 904 9.9E-47
CDD cd00613 GDC-P IPR020581 Glycine cleavage system P protein 68 445 0.0
Pfam PF02347 Glycine cleavage system P-protein IPR020581 Glycine cleavage system P protein 482 743 5.6E-10
SUPERFAMILY SSF53383 PLP-dependent transferases IPR015424 Pyridoxal phosphate-dependent transferase 466 952 2.16E-107
FunFam G3DSA:3.90.1150.10:FF:000007 Glycine dehydrogenase (decarboxylating), mitochondrial - - 766 904 6.3E-73

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.